Pub. Date : 1996 Oct
PMID : 8957747
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The effect of long-term prednisone treatment on growth hormone and insulin-like growth factor-1. | Prednisone | growth hormone 1 | Homo sapiens |
2 | Basal GH levels were frequently undetectable, but during treatment GH values were lower in the prednisone group (median of detectable values 4.0 mU/L [range 2.0-26.0]) than in controls (11.8 [2.8-44.0]; p < 0.01). | Prednisone | growth hormone 1 | Homo sapiens |
3 | In conclusion, long-term prednisone treatment is associated with suppressed GH levels and with an increase in total IGF-1 levels. | Prednisone | growth hormone 1 | Homo sapiens |
4 | This suggests that prednisone can disrupt the GH/IGF 1 axis. | Prednisone | growth hormone 1 | Homo sapiens |