Title : The effect of long-term prednisone treatment on growth hormone and insulin-like growth factor-1.

Pub. Date : 1996 Oct

PMID : 8957747






4 Functional Relationships(s)
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1 The effect of long-term prednisone treatment on growth hormone and insulin-like growth factor-1. Prednisone growth hormone 1 Homo sapiens
2 Basal GH levels were frequently undetectable, but during treatment GH values were lower in the prednisone group (median of detectable values 4.0 mU/L [range 2.0-26.0]) than in controls (11.8 [2.8-44.0]; p < 0.01). Prednisone growth hormone 1 Homo sapiens
3 In conclusion, long-term prednisone treatment is associated with suppressed GH levels and with an increase in total IGF-1 levels. Prednisone growth hormone 1 Homo sapiens
4 This suggests that prednisone can disrupt the GH/IGF 1 axis. Prednisone growth hormone 1 Homo sapiens