Pub. Date : 1996 Dec 13
PMID : 8954910
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytokine and low-level nitric oxide prestimulation block p53 accumulation and apoptosis of RAW 264.7 macrophages. | Nitric Oxide | tumor protein p53 | Homo sapiens |
| 2 | Upregulation of protective mechanisms in response to non-lethal NO concentrations or by LPS, cytokine pre-stimulation may redirect the ability of nitric oxide to upregulate p53 and to initiate macrophage apoptosis, thereby modulating cellular susceptibility towards NO-intoxication. | Nitric Oxide | tumor protein p53 | Homo sapiens |