Title : Functional differences between rabbit and human Na(+)-dicarboxylate cotransporters, NaDC-1 and hNaDC-1.

Pub. Date : 1996 Nov

PMID : 8946005






3 Functional Relationships(s)
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1 The rabbit and human Na(+)-dicarboxylate cotransporters, NaDC-1 and hNaDC-1, were expressed in Xenopus oocytes, and the transport of succinate, citrate, and glutarate was compared. Citric Acid solute carrier family 13 member 2 Homo sapiens
2 At pH 7.5, the K(m) value for citrate was 0.9 mM in the rabbit NaDC-1 and 7 mM in the human hNaDC-1. Citric Acid solute carrier family 13 member 2 Homo sapiens
3 At pH 5.5, the K(m) value for citrate decreased to 1.2 mM in hNaDC-1 and decreased to 0.3 mM in the rabbit transporter. Citric Acid solute carrier family 13 member 2 Homo sapiens