Title : Mutation of the pleckstrin homology domain of Bruton's tyrosine kinase in immunodeficiency impaired inositol 1,3,4,5-tetrakisphosphate binding capacity.

Pub. Date : 1996 Nov 29

PMID : 8939985






1 Functional Relationships(s)
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Protein Name
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1 In contrast, a gain-of-function mutant called Btk*, which carries a E41K mutation in the PH domain, binds IP6 with two times higher affinity than the wild type. Phytic Acid Bruton tyrosine kinase Homo sapiens