Pub. Date : 1996 Apr
PMID : 8928731
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Increased synthesis of high-molecular-weight cPLA2 mediates early UV-induced PGE2 in human skin. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |
| 2 | The 105-kDa cPLA2 was demonstrated to be the critical enzyme in UV-induced PGE2 synthesis and erythema in the first 6 h postirradiation. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |
| 3 | This increase in cPLA2 synthesis and activation also closely correlated with increased PGE2 synthesis and [3H]arachidonic acid release and was effectively blocked by both an S-oligonucleotide antisense to cPLA2 and methyl arachidonate fluorophosphate, a specific inhibitor of cPLA2. | Dinoprostone | phospholipase A2 group IVA | Homo sapiens |