Title : Dioxin induces transcription of fos and jun genes by Ah receptor-dependent and -independent pathways.

Pub. Date : 1996 Nov

PMID : 8917696






1 Functional Relationships(s)
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1 In a previous study, we have shown that treatment of mouse hepatoma cells with TCDD or B(a)P results in an increase in mRNA levels of the immediate-early protooncogenes c-fos, c-jun, junB, and junD, and the concomitant increase of the DNA-binding activity of the transcription factor AP-1, a dimer of FOS and JUN proteins. Benzo(a)pyrene jun D proto-oncogene Mus musculus