Pub. Date : 1996 Nov
PMID : 8915775
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NaF increased cellular reduction of nitroblue tetrazolium (NBT), and this effect was strongly augmented by 1,25(OH)2D3. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 2 | Furthermore, NaF increased expression of CD11b and CD66b, and this stimulation was enhanced by adding 1,25(OH)2D3. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 3 | Similarly, NaF stimulated the production of interleukin 1 alpha (IL-1 alpha), IL-6, and tumor necrosis factor-alpha, and 1,25(OH)2D3 again strongly enhanced these effects. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 4 | These additional findings together with the observed slow onset (24-48 h) of NaF and 1,25(OH)2D3 interaction strongly suggest that 1,25(OH)2D3 acts as a cofactor with NaF primarily through interaction with an endogenous NaF-induced cyclo-oxygenase product(s), quite possibly PGE2 itself. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 5 | These additional findings together with the observed slow onset (24-48 h) of NaF and 1,25(OH)2D3 interaction strongly suggest that 1,25(OH)2D3 acts as a cofactor with NaF primarily through interaction with an endogenous NaF-induced cyclo-oxygenase product(s), quite possibly PGE2 itself. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 6 | These additional findings together with the observed slow onset (24-48 h) of NaF and 1,25(OH)2D3 interaction strongly suggest that 1,25(OH)2D3 acts as a cofactor with NaF primarily through interaction with an endogenous NaF-induced cyclo-oxygenase product(s), quite possibly PGE2 itself. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 7 | These additional findings together with the observed slow onset (24-48 h) of NaF and 1,25(OH)2D3 interaction strongly suggest that 1,25(OH)2D3 acts as a cofactor with NaF primarily through interaction with an endogenous NaF-induced cyclo-oxygenase product(s), quite possibly PGE2 itself. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 8 | These additional findings together with the observed slow onset (24-48 h) of NaF and 1,25(OH)2D3 interaction strongly suggest that 1,25(OH)2D3 acts as a cofactor with NaF primarily through interaction with an endogenous NaF-induced cyclo-oxygenase product(s), quite possibly PGE2 itself. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 9 | Such a mechanism for NaF and 1,25(OH)2D3 interaction would be strongly analogous to the interaction we have recently demonstrated between 1,25(OH)2D3 and PGE1 on the differentiation of HL-60 cells. | Calcitriol | C-X-C motif chemokine ligand 8 | Homo sapiens |