Pub. Date : 1996 Sep
PMID : 8906565
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recent studies indicate that PLD activities require a lipid cofactor, phosphatidylinositol 4,5-bisphosphate (PIP2). | Phosphatidylinositol 4,5-Diphosphate | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 2 | Recent studies indicate that PLD activities require a lipid cofactor, phosphatidylinositol 4,5-bisphosphate (PIP2). | Phosphatidylinositol 4,5-Diphosphate | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 3 | Addition of PIP2 at physiological concentrations stimulates both membrane-associated and partially purified PLD activity. | Phosphatidylinositol 4,5-Diphosphate | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 4 | Neomycin, a high affinity ligand of PIP2, inhibits membrane PLD activity, presumably by binding to endogenous PIP2. | Phosphatidylinositol 4,5-Diphosphate | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 5 | Neomycin, a high affinity ligand of PIP2, inhibits membrane PLD activity, presumably by binding to endogenous PIP2. | Phosphatidylinositol 4,5-Diphosphate | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |
| 6 | These results indicate that PIP2 synthesis is required for G protein- and protein kinase C-mediated activation of PLD in the cells. | Phosphatidylinositol 4,5-Diphosphate | glycosylphosphatidylinositol specific phospholipase D1 | Homo sapiens |