Pub. Date : 1996 Aug 12
PMID : 8905718
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The reduction in 3-[4,5-dimethylthiazol]-2,5-diphenyltetrazolium bromide (MTT) to a coloured formazan compound by cultured cells has been extensively used as an in vitro model for understanding neurobiological mechanisms involved in amyloid beta-protein (A beta-mediated cell death. | monooxyethylene trimethylolpropane tristearate | amyloid beta precursor protein | Homo sapiens |
| 2 | In primary cultures of astrocytes, very low concentrations of aggregated A beta 1-4C, but not A beta 4C-1, produced a significant inhibition in the reduction of the dye MTT. | monooxyethylene trimethylolpropane tristearate | amyloid beta precursor protein | Homo sapiens |
| 3 | These results suggest that even though inhibition of MTT reduction represents an early indicator of the A beta 1-4C mediated cell injury, without other corroborating evidence, it should not be used as a measure of cell death. | monooxyethylene trimethylolpropane tristearate | amyloid beta precursor protein | Homo sapiens |