Title : Tissue-specific growth suppression and chemosensitivity promotion in human hepatocellular carcinoma cells by retroviral-mediated transfer of the wild-type p53 gene.

Pub. Date : 1996 Nov

PMID : 8903408






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Introduction of WT-p53 into AFP-positive HCC cells by retroviral infection markedly inhibited their clonal growth in monolayer and soft agar cultures, and increased the sensitivity of these cells to the chemotherapeutic drug, cisplatin. Cisplatin tumor protein p53 Homo sapiens