Title : Glucose and pyruvate regulate cytokine-induced nitric oxide production by cardiac myocytes.

Pub. Date : 1996 Oct

PMID : 8897830






3 Functional Relationships(s)
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1 Removal of glucose from the media partially inhibited IL-1 beta-stimulated nitrite (NO2-) production [8.1 +/- 0.3 vs. 4.4 +/- 0.6 nmol. Nitrogen Dioxide interleukin 1 beta Rattus norvegicus
2 The glycolytic inhibitor 2-deoxy-D-glucose (2-DG) completely inhibited IL-1 beta-stimulated NO2- production [0.7 +/- 0.5 nmol. Nitrogen Dioxide interleukin 1 beta Rattus norvegicus
3 The addition of the glycolytic end product, pyruvate, completely blocked the 2-DG inhibition of IL-1 beta-stimulated NO2- production [7.4 +/- 0.4 nmol. Nitrogen Dioxide interleukin 1 beta Rattus norvegicus