Title : Selective potentiation of cytokine expression in human whole blood by murabutide, a muramyl dipeptide analogue.

Pub. Date : 1996 Aug

PMID : 8894442






3 Functional Relationships(s)
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1 Thus, in the presence of IL-2, IL-6, IL-3 or granulocyte-macrophage colony-stimulating factor (GM-CSF), the level of cytokines induced by murabutide was enhanced with no change in the other cytokines profile. murabutide colony stimulating factor 2 Homo sapiens
2 Thus, in the presence of IL-2, IL-6, IL-3 or granulocyte-macrophage colony-stimulating factor (GM-CSF), the level of cytokines induced by murabutide was enhanced with no change in the other cytokines profile. murabutide colony stimulating factor 2 Homo sapiens
3 IL-3 and GM-CSF were more potent in increasing the murabutide-induced response, eliciting synergistic effects on IL-8 and IL-1Ra production, at both the mRNA accumulation and the protein release. murabutide colony stimulating factor 2 Homo sapiens