Title : Inhibition of steroid C17(20) lyase with C-17-heteroaryl steroids.

Pub. Date : 1996 Sep

PMID : 8894099






3 Functional Relationships(s)
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Protein Name
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1 Inhibition of steroid C17(20) lyase with C-17-heteroaryl steroids. Steroids cytokine like 1 Homo sapiens
2 Steroids bearing a heteroaromatic substituent at C-17 were designed as inhibitors of C17(20) lyase. Steroids cytokine like 1 Homo sapiens
3 The position of the heterocycle with respect to the steroid skeleton was determined to be important for optimum affinity and, in general, compounds with the heterocycle attached to a trigonal center at C-17, had the best affinity for C17(20) lyase. Steroids cytokine like 1 Homo sapiens