Title : Effects of progesterone on serum levels of IGF-1 and on femur IGF-1 mRNA in ovariectomized rats.

Pub. Date : 1996 Oct

PMID : 8889839






2 Functional Relationships(s)
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1 The present studies describe the in vivo effects of estradiol, progesterone, or both on IGF-1 mRNA abundance in bone, serum IGF-1 levels, and bone formation. Progesterone insulin-like growth factor 1 Rattus norvegicus
2 IGF-1 transcripts 7.5 and 0.8 kb were decreased by 72 and 29%, respectively, in estrogen-treated and increased by 44 and 43%, respectively, in progesterone-treated rats compared with vehicle-treated OVX rats. Progesterone insulin-like growth factor 1 Rattus norvegicus