Title : Complement activation by myeloperoxidase products released from stimulated human polymorphonuclear leukocytes.

Pub. Date : 1996 Aug

PMID : 8877407






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Stimulated PMN release H2O2 and MPO that produces hypochlorite and secondarily various chloramines. Hypochlorous Acid myeloperoxidase Homo sapiens
2 These findings indicate that the C5 activating agent was produced by stimulated PMN through MPO-generated hypochlorite, trapped as taurine chloramine. Hypochlorous Acid myeloperoxidase Homo sapiens
3 In the absence of added taurine the hypochlorite formed by MPO oxidized endogenous amines that also activated C5. Hypochlorous Acid myeloperoxidase Homo sapiens