Title : Increased granulocyte-macrophage colony-stimulating factor mRNA instability in cord versus adult mononuclear cells is translation-dependent and associated with increased levels of A + U-rich element binding factor.

Pub. Date : 1996 Oct 15

PMID : 8874185






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Translational inhibition by cycloheximide (CHX) significantly increased GM-CSF mRNA accumulation and half-life by three-fold in activated cord MNC, but had a minimal effect in activated adult MNC as compared with PMA + PHA alone. Cycloheximide colony stimulating factor 2 Homo sapiens
2 Translational inhibition by cycloheximide (CHX) significantly increased GM-CSF mRNA accumulation and half-life by three-fold in activated cord MNC, but had a minimal effect in activated adult MNC as compared with PMA + PHA alone. Cycloheximide colony stimulating factor 2 Homo sapiens