Title : Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells.

Pub. Date : 1996 Jul

PMID : 8870819






5 Functional Relationships(s)
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1 Effect of biotin on glucokinase activity, mRNA expression and insulin release in cultured beta-cells. Biotin glucokinase Rattus norvegicus
2 Biotin is known to influence hepatic glucokinase (GK) expression both at a transcriptional and at a translational level. Biotin glucokinase Rattus norvegicus
3 Biotin is known to influence hepatic glucokinase (GK) expression both at a transcriptional and at a translational level. Biotin glucokinase Rattus norvegicus
4 The aim of the present paper was to investigate the effect of biotin on pancreatic GK. Biotin glucokinase Rattus norvegicus
5 Results demonstrated that biotin has a biphasic effect on GK mRNA expression, being stimulatory after short-term treatment and inhibitory after longterm treatment. Biotin glucokinase Rattus norvegicus