Title : The angiotensin I-converting enzyme inhibitor, cilazapril inhibits the platelet-derived growth factor B chain expression in glomeruli of spontaneously hypertensive rats.

Pub. Date : 1995 Sep-Oct

PMID : 8869081






2 Functional Relationships(s)
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1 The PDGF B chain expression was suppressed by treatment with cilazapril (2.5-fold) as compared with nontreated SHR. Cilazapril platelet derived growth factor subunit B Rattus norvegicus
2 These findings indicate that the expression of PDGF B chain in the glomerulus preceded the appearance of histological changes in SHR and that the administration of cilazapril inhibited the expression of PDGF B chain without affecting the glomerular size. Cilazapril platelet derived growth factor subunit B Rattus norvegicus