Pub. Date : 1996 Aug
PMID : 8866476
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We previously reported that oxidative damage in yeast lacking copper/zinc superoxide dismutase (SOD1) can be alleviated through mutations in PMR1, encoding a calcium P-type ATPase homologue that also functions in manganese homeostasis. | Manganese | Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 | Saccharomyces cerevisiae S288C |
| 2 | In an attempt to further understand the relationship between manganese ions, PMR1 and SOD1, we conducted a search for manganese homeostasis genes that interact with PMR1. | Manganese | Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 | Saccharomyces cerevisiae S288C |
| 3 | In an attempt to further understand the relationship between manganese ions, PMR1 and SOD1, we conducted a search for manganese homeostasis genes that interact with PMR1. | Manganese | Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 | Saccharomyces cerevisiae S288C |
| 4 | A genomic library was screened for genes that, when overexpressed, suppress the manganese hypersensitivity associated with pmr1 mutations. | Manganese | Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 | Saccharomyces cerevisiae S288C |
| 5 | A single clone was isolated that reduced manganese toxicity in both the pmr1 mutant and PMR1 wild-type yeast. | Manganese | Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 | Saccharomyces cerevisiae S288C |
| 6 | A single clone was isolated that reduced manganese toxicity in both the pmr1 mutant and PMR1 wild-type yeast. | Manganese | Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 | Saccharomyces cerevisiae S288C |
| 7 | Our studies indicate that, like PMR1, CCC1 functions in the homeostasis of both calcium and manganese ions. | Manganese | Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 | Saccharomyces cerevisiae S288C |
| 8 | We provide a model in which Ccc1p and Pmr1p work together to control the intracellular partitioning of manganese ions. | Manganese | Ca(2+)/Mn(2+)-transporting P-type ATPase PMR1 | Saccharomyces cerevisiae S288C |