Pub. Date : 1996 Summer
PMID : 8856738
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Systemic application of pyrethroid insecticides evokes differential expression of c-Fos and c-Jun proteins in rat brain. | Pyrethrins | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 2 | Expression of the c-Fos and c-Jun transcription factor was investigated by immunocytochemistry in the thalamus, hypothalamus, hippocampus and cortex of adult rats following intraperitoneal application of proconvulsant doses of the pyrethroid insecticides, cypermethrin and permethrin. | Pyrethrins | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |
| 3 | Our results demonstrate that the neurotoxic effects of pyrethroid insecticides comprise molecular genetic alterations in the brain such as early and lasting induction of Fos and Jun transcription factor proteins. | Pyrethrins | Fos proto-oncogene, AP-1 transcription factor subunit | Rattus norvegicus |