Title : Calcitonin gene related peptide as inhibitory neurotransmitter in the ureter.

Pub. Date : 1995 Jul

PMID : 8846441






2 Functional Relationships(s)
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1 Electrical stimulation of intramural nerves in the guinea-pig ureter produces a transient membrane hyperpolarization, which is blocked by glibenclamide or by capsaicin pretreatment, enhanced in a low-K medium, and inhibited by a CGRP receptor antagonist. Capsaicin calcitonin related polypeptide alpha Homo sapiens
2 The refractory period of the guinea-pig ureter is markedly and similarly reduced by capsaicin pretreatment or administration of a CGRP receptor antagonist, indicating that endogenous CGRP can modulate the maximal frequency of ureteral peristalsis. Capsaicin calcitonin related polypeptide alpha Homo sapiens