Pub. Date : 1995 Jul
PMID : 8846404
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In phenobarbitone-anesthetized rats the effects of interleukin 1 beta (IL-1 beta) and tumor necrosis factors (TNFs) were examined on the capsaicin-induced increase of plantar cutaneous blood flow in the rat hind paw as measured by laser Doppler flowmetry. | Capsaicin | interleukin 1 beta | Rattus norvegicus |
2 | In phenobarbitone-anesthetized rats the effects of interleukin 1 beta (IL-1 beta) and tumor necrosis factors (TNFs) were examined on the capsaicin-induced increase of plantar cutaneous blood flow in the rat hind paw as measured by laser Doppler flowmetry. | Capsaicin | interleukin 1 beta | Rattus norvegicus |
3 | IL-1 beta was without effect on blood flow by its own but dose dependently enhanced the hyperemia due to capsaicin (0.3 microgram). | Capsaicin | interleukin 1 beta | Rattus norvegicus |
4 | did not alter the capsaicin-induced vasodilatation but prevented IL-1 beta (50 pg) from augmenting the hyperemic response to capsaicin. | Capsaicin | interleukin 1 beta | Rattus norvegicus |
5 | Systemic pretreatment with a neurotoxic dose of capsaicin reduced the capsaicin-induced hyperemia and prevented the facilitatory effect of IL-1 beta. | Capsaicin | interleukin 1 beta | Rattus norvegicus |
6 | These data indicate that IL-1 beta but not TNF enhances the cutaneous hyperemic response to capsaicin. | Capsaicin | interleukin 1 beta | Rattus norvegicus |