Title : A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages.

Pub. Date : 1996 Oct 1

PMID : 8839832






6 Functional Relationships(s)
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1 A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages. Tetradecanoylphorbol Acetate TNF receptor superfamily member 8 Homo sapiens
2 We identified and cloned cDNAs for two novel CD30 mRNAs of 2.3 kb that are induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) in the human myeloid leukemia cell line HL-60. Tetradecanoylphorbol Acetate TNF receptor superfamily member 8 Homo sapiens
3 We identified and cloned cDNAs for two novel CD30 mRNAs of 2.3 kb that are induced by 12-O-tetradecanoylphorbol 13-acetate (TPA) in the human myeloid leukemia cell line HL-60. Tetradecanoylphorbol Acetate TNF receptor superfamily member 8 Homo sapiens
4 Northern blots detected the expression of CD30v transcripts only in the lung and the TPA-stimulated HL-60 cell line. Tetradecanoylphorbol Acetate TNF receptor superfamily member 8 Homo sapiens
5 Immunoblotting analysis with HCD30C1, a rabbit polyclonal antibody raised against the cytoplasmic domain of CD30 protein, detected proteins with an apparent Mr 25 kD expressed in TPA-stimulated HL-60 and COS-7 cells that were transfected with both types of CD30v cDNAs. Tetradecanoylphorbol Acetate TNF receptor superfamily member 8 Homo sapiens
6 Immunoblotting analysis with HCD30C1, a rabbit polyclonal antibody raised against the cytoplasmic domain of CD30 protein, detected proteins with an apparent Mr 25 kD expressed in TPA-stimulated HL-60 and COS-7 cells that were transfected with both types of CD30v cDNAs. Tetradecanoylphorbol Acetate TNF receptor superfamily member 8 Homo sapiens