Title : Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase.

Pub. Date : 1996 Oct

PMID : 8837615






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1 Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase. Caffeine tumor protein p53 Homo sapiens
2 We demonstrate that abrogation of G2 arrest by caffeine-mediated activation of p34cdc2 kinase results in the selective sensitization of p53-deficient primary and tumor cells to irradiation-induced apoptosis. Caffeine tumor protein p53 Homo sapiens