Title : Regulation of capacitative calcium influx in cultured human mesangial cells: roles of protein kinase C and calmodulin.

Pub. Date : 1996 Jul

PMID : 8829112






1 Functional Relationships(s)
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1 Moreover, the calmodulin inhibitors calmidazolium (10 uM), trifluoperazine (0.1 mM), or W-7 (0.1 mM) significantly inhibited AngII- or ionomycin-activated iCRAC (+106 +/- 38/229 +/- 53, +58 +/- 9/195 +/- 29, +161 +/- 38/180 +/- 40% at 1/10 mM (Ca2+)e, all P < 0.05), but did not affect basal Ca2+ entry, consistent with a direct role of cytoplasmic Ca2+ in the regulation of ion gating. W 7 angiotensinogen Homo sapiens