Title : Interleukin-1 alpha and -beta modulation of luteinized human granulosa cell oestrogen and progesterone biosynthesis.

Pub. Date : 1995 Dec

PMID : 8822445






4 Functional Relationships(s)
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1 Interleukin-1 alpha and -beta modulation of luteinized human granulosa cell oestrogen and progesterone biosynthesis. Progesterone interleukin 1 alpha Homo sapiens
2 This study was designed to test the hypothesis that interleukin-1 alpha (IL-1 alpha) and beta directly affect progesterone, and oestradiol production in cultures of purified human granulosa cells. Progesterone interleukin 1 alpha Homo sapiens
3 This study was designed to test the hypothesis that interleukin-1 alpha (IL-1 alpha) and beta directly affect progesterone, and oestradiol production in cultures of purified human granulosa cells. Progesterone interleukin 1 alpha Homo sapiens
4 Our results indicate that progesterone synthesis by basal and human chorionic gonadotrophin (HCG)-stimulated granulosa cells co-cultured with white blood cells was inhibited by 5.0 ng/ml of IL-1 alpha and IL-1 beta at 48 h of culture. Progesterone interleukin 1 alpha Homo sapiens