Title : Structure-activity relationships among desmethyl derivatives of neuroleptics and antidepressants for substrate specificty to indolethylamine N-methyltransferase from rabbit lung.

Pub. Date : 1976

PMID : 8818






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Desmethylperazine (norperazine) and desmethylprochlorperazine (norprochlorperazine), like nor1- and nor2chlorpromazine, are excellent substrates for indolethylamine N-methyltransferase (NMT) and also inhibit the formation of dimethyltryptamine (DMT) from N-methyl-tryptamine (NMT). N,N-Dimethyltryptamine indolethylamine N-methyltransferase Oryctolagus cuniculus
2 Desmethylperazine (norperazine) and desmethylprochlorperazine (norprochlorperazine), like nor1- and nor2chlorpromazine, are excellent substrates for indolethylamine N-methyltransferase (NMT) and also inhibit the formation of dimethyltryptamine (DMT) from N-methyl-tryptamine (NMT). N,N-Dimethyltryptamine indolethylamine N-methyltransferase Oryctolagus cuniculus