Title : Crystallographic Analysis of Antigen-Antibody Complexes: End-on Insertion of Ligands in Antibodies-CDR3 Loops as Arbiters

Pub. Date : 1996 Jun

PMID : 8812710






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the 4-4-20 Fab, the CDR3 loops provide scaffolding for the high-affinity binding of fluorescein and shield the ligand from bulk solvent in the interdomain space above and below the very compact binding slot. Fluorescein FA complementation group B Homo sapiens