Pub. Date : 1996 Jul
PMID : 8809407
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p21WAF1/CIP1/SDI1 is elevated through a p53-independent pathway by mimosine. | Mimosine | tumor protein p53 | Homo sapiens |
| 2 | In this study, we showed that mimosine can increase both p21 mRNA and protein levels, indirectly inhibit cyclin E-associated kinase activity without affecting the cyclin E protein level, block human breast cancer cells (21PT) in the late G1 phase of the cell cycle, and induce a p53-independent p21 pathway in these cells. | Mimosine | tumor protein p53 | Homo sapiens |