Title : Lack of efficacy of 5-HT2A receptor antagonists to reduce brain damage after 3 minutes of transient global cerebral ischaemia in gerbils.

Pub. Date : 1995

PMID : 8808177






1 Functional Relationships(s)
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1 Stimulation of the 5-HT2A receptors by serotonin has been reported to exert an excitatory effect on neocortical neurons in rats and mice, to facilitate ischaemia-induced release of excitatory amino acids and to mediate the vasomotor constrictor component of the response of blood vessels to 5-HT. Serotonin 5-hydroxytryptamine receptor 2A Rattus norvegicus