Title : The cystic fibrosis transmembrane conductance regulator mediates transepithelial fluid secretion by human autosomal dominant polycystic kidney disease epithelium in vitro.

Pub. Date : 1996 Jul

PMID : 8807590






2 Functional Relationships(s)
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1 Utilizing several antibodies to hCFTR, immunocytochemistry and confocal fluorescence microscopy localized an immunoreactive protein primarily in the apical region of forskolin-stimulated ADPKD cells grown on permeable supports. Colforsin CF transmembrane conductance regulator Homo sapiens
2 On the basis of these results we suggest that CFTR is a major mediator of forskolin-stimulated chloride and fluid secretion by epithelial cells of human polycystic kidneys in vitro. Colforsin CF transmembrane conductance regulator Homo sapiens