Pub. Date : 1996 Aug 1
PMID : 8806713
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The results show that both rat and human UGT1.1 catalyze the glucuronidation of opioids with a relative reactivity of buprenorphine > > nalorphine approximately naltrexone. | Buprenorphine | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |
| 2 | Comparison of glucuronidation activities in livers from Crigler-Najjar type 1 patients and normal patients indicates that UGT1.1 catalyzes at least 75% of buprenorphine conjugation in normal human liver. | Buprenorphine | UDP glucuronosyltransferase family 1 member A1 | Homo sapiens |