Pub. Date : 1996 Sep 13
PMID : 8806659
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | To delineate the mechanism of inhibition of microsomal lipid peroxidation by GSH + GSSG, we examined the effects of these compounds on cytochrome P-450 reductase (EC 1.6.2.4), an important component of the NADPH-dependent enzymatic lipid peroxidation system. | NADP | cytochrome p450 oxidoreductase | Rattus norvegicus |
2 | We speculate that one possible mechanism for the inhibition of NADPH-dependent lipid peroxidation by GSH + GSSG is, in part, due to inhibition of NADPH cytochrome P-450 reductase, thus affecting the initiation phase of lipid peroxidation. | NADP | cytochrome p450 oxidoreductase | Rattus norvegicus |