Title : Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

Pub. Date : 1996 Sep 19

PMID : 8805703






1 Functional Relationships(s)
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Protein Name
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1 SHIP, by hydrolysing the 5-phosphate of phosphatidylinositol(3,4,5)P3 and inositol(1,3,4,5)P4, suggests a mechanism by which Fc(gamma)RIIB can inhibit calcium influx and downstream responses triggered by immune receptors. Calcium inositol polyphosphate-5-phosphatase D Homo sapiens