Title : Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits.

Pub. Date : 1996 Sep 15

PMID : 8805593






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BACKGROUND: The essential enzyme dUTP pyrophosphatase (dUTPase) is exquisitely specific for dUTP and is critical for the fidelity of DNA replication and repair. deoxyuridine triphosphate Deoxyuridine triphosphatase Drosophila melanogaster
2 dUTPase hydrolyzes dUTP to dUMP and pyrophosphate, simultaneously reducing dUTP levels and providing the dUMP for dTTP biosynthesis. deoxyuridine triphosphate Deoxyuridine triphosphatase Drosophila melanogaster