Title : G protein-coupled receptor kinase GRK2 is a phospholipid-dependent enzyme that can be conditionally activated by G protein betagamma subunits.

Pub. Date : 1996 Sep 13

PMID : 8798423






2 Functional Relationships(s)
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1 Among lipids tested, lipid inositol phosphates, PIP2 and phosphatidylinositol 4-monophosphate, were found to be the most potent activators of GRK2 and were the only lipids that regulated GRK2 in a complex biphasic manner. Inositol Phosphates G protein-coupled receptor kinase 2 Homo sapiens
2 Among lipids tested, lipid inositol phosphates, PIP2 and phosphatidylinositol 4-monophosphate, were found to be the most potent activators of GRK2 and were the only lipids that regulated GRK2 in a complex biphasic manner. Inositol Phosphates G protein-coupled receptor kinase 2 Homo sapiens