Pub. Date : 1996
PMID : 8790719
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Molecular mechanism of thymidylate synthase-catalyzed reaction and interaction of the enzyme with 2- and/or 4-substituted analogues of dUMP and 5-fluoro-dUMP. | 2'-deoxyuridylic acid | thymidylate synthetase | Homo sapiens |
2 | With two dUMP analogues, 5-fluoro-dUMP (FdUMP) and 5-(trifluoromethyl)-dUMP (CF3dUMP), strong thymidylate synthase inhibitors and active forms of drugs, the inhibition mechanism is based on the reaction mechanism. | 2'-deoxyuridylic acid | thymidylate synthetase | Homo sapiens |