Title : Dual role of heme oxygenase in epithelial cell injury: contrasting effects of short-term and long-term exposure to oxidant stress.

Pub. Date : 1996 Sep

PMID : 8783636






3 Functional Relationships(s)
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1 BSC-1 cells adapted by long-term exposure to H2O2 exhibited a twofold increase in basal HO activity and expression of HO-1 mRNA as compared with their wild-type counterparts. Hydrogen Peroxide heme oxygenase 1 Homo sapiens
2 Exposure of both adapted and wild-type BSC-1 cells to H2O2 induced HO-1 mRNA. Hydrogen Peroxide heme oxygenase 1 Homo sapiens
3 In conclusion, two interrelated stressors, H2O2 and hemin, produced a stimulation of HO-1, and this was associated with a reduction in the viability of BSC-1 cells. Hydrogen Peroxide heme oxygenase 1 Homo sapiens