Title : Characterization of acid extrusion mechanisms in cultured fetal rat hippocampal neurones.

Pub. Date : 1996 Jun 1

PMID : 8782109






5 Functional Relationships(s)
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1 Recovery of pHi from an acid load imposed in the absence of HCO3- was dependent on external Na+. Bicarbonates glucose-6-phosphate isomerase Rattus norvegicus
2 Addition of HCO3- to the perfusion medium increased the rate of pHi recovery from an acid load at room temperature but not at 37 degrees C. In the presence of HCO3-, DIDS slowed the rate of recovery of pHi from an acid load at both room temperature and at 37 degrees C. 5. Bicarbonates glucose-6-phosphate isomerase Rattus norvegicus
3 Addition of HCO3- to the perfusion medium increased the rate of pHi recovery from an acid load at room temperature but not at 37 degrees C. In the presence of HCO3-, DIDS slowed the rate of recovery of pHi from an acid load at both room temperature and at 37 degrees C. 5. Bicarbonates glucose-6-phosphate isomerase Rattus norvegicus
4 Addition of HCO3- to the perfusion medium increased the rate of pHi recovery from an acid load at room temperature but not at 37 degrees C. In the presence of HCO3-, DIDS slowed the rate of recovery of pHi from an acid load at both room temperature and at 37 degrees C. 5. Bicarbonates glucose-6-phosphate isomerase Rattus norvegicus
5 Recovery of pHi following an imposed intracellular acidification to pH < 6.5 could occur in the absence of external Na+, providing that HCO3- was present in the perfusate. Bicarbonates glucose-6-phosphate isomerase Rattus norvegicus