Title : Neuronal metabolism of branched-chain amino acids: flux through the aminotransferase pathway in synaptosomes.

Pub. Date : 1996 May

PMID : 8780046






4 Functional Relationships(s)
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1 The BCAA amino-transferase reaction also proceeded in the "reverse" direction [alpha-ketoisocaproate (KIC) + glutamate-->leucine + alpha-ketoglutarate]. Leucine AT-rich interaction domain 4B Homo sapiens
2 The BCAA transaminase mediated not only the bidrectional transfer of amino groups between leucine or valine and glutamate, but also the direct transfer of nitrogen between leucine and valine. Leucine AT-rich interaction domain 4B Homo sapiens
3 The BCAA transaminase mediated not only the bidrectional transfer of amino groups between leucine or valine and glutamate, but also the direct transfer of nitrogen between leucine and valine. Leucine AT-rich interaction domain 4B Homo sapiens
4 It is suggested that in synaptosomes the BCAA transaminase (a) functions predominantly in the direction of leucine formation and (b) maintains a constant ratio of BCAAs and ketoacids to one other. Leucine AT-rich interaction domain 4B Homo sapiens