Pub. Date : 1996 Mar
PMID : 8778231
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Adrenocorticotropin (ACTH) treatment increased c-myc mRNA accumulation dose- and time-dependently up to more than 5-fold (on average), with the maximal effect at 2 h. (Bu)2cAMP and 12-O-tetradecanoyl phorbol 13-acetate (TPA) also induced c-myc gene expression. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | Adrenocorticotropin (ACTH) treatment increased c-myc mRNA accumulation dose- and time-dependently up to more than 5-fold (on average), with the maximal effect at 2 h. (Bu)2cAMP and 12-O-tetradecanoyl phorbol 13-acetate (TPA) also induced c-myc gene expression. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 3 | H-7 totally abolished ACTH-, TPA- and (Bu)2cAMP-induced c-myc expression, while staurosporine inhibited the stimulatory effects of ACTH and TPA, and HA1004 weakly inhibited the effects of ACTH and (Bu)2cAMP. | Tetradecanoylphorbol Acetate | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |