Title : A nuclear gene encoding mitochondrial proline dehydrogenase, an enzyme involved in proline metabolism, is upregulated by proline but downregulated by dehydration in Arabidopsis.

Pub. Date : 1996 Aug

PMID : 8776899






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A nuclear gene encoding mitochondrial proline dehydrogenase, an enzyme involved in proline metabolism, is upregulated by proline but downregulated by dehydration in Arabidopsis. Proline Methylenetetrahydrofolate reductase family protein Arabidopsis thaliana
2 Sequence analysis of an Arabidopsis cDNA clone, ERD5 (for early responsive to dehydration stress), isolated from plants dehydrated for 1 hr, revealed that it encodes a protein with identity to products of the yeast PUT1 (for proline utilization) gene (23.6% over 364 amino acids) and the Drosophila sluggish-A gene (34.5% over 255 amino acids). Proline Methylenetetrahydrofolate reductase family protein Arabidopsis thaliana
3 Immunologically, we showed that the product of ERD5 is localized in the mitochondrial fraction and accumulates in response to proline in cultured cells. Proline Methylenetetrahydrofolate reductase family protein Arabidopsis thaliana
4 Fusion genes for ERD5 and PUT1 complemented a put1 mutant of yeast, allowing put1 to grow with proline as the source of nitrogen. Proline Methylenetetrahydrofolate reductase family protein Arabidopsis thaliana