Pub. Date : 1996 Jun
PMID : 8776730
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using a steroid-responsive reporter construct, we found that GA inhibited the dexamethasone-dependent transactivating activity of GR in transfected cells. | Steroids | nuclear receptor subfamily 3 group C member 1 | Homo sapiens |
| 2 | Overall, these findings provide direct pharmacological evidence that hsp90 function is required to maintain both the hormone-binding activity and stability of the GR protein in intact cells and suggest that hsp90 function may provide a novel target for the modulation of steroid hormone signaling. | Steroids | nuclear receptor subfamily 3 group C member 1 | Homo sapiens |