Pub. Date : 1996 Aug
PMID : 8770045
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have recently shown that taurocholate (TCA) represses the transcriptional activity of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme of the bile acid biosynthetic pathway, through a protein kinase C (PKC)-dependent mechanism in primary cultures of rat hepatocytes. | Taurocholic Acid | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 2 | We have recently shown that taurocholate (TCA) represses the transcriptional activity of cholesterol 7 alpha-hydroxylase, the rate-limiting enzyme of the bile acid biosynthetic pathway, through a protein kinase C (PKC)-dependent mechanism in primary cultures of rat hepatocytes. | Taurocholic Acid | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |
| 3 | The calcium-independent PKC isoforms may mediate the repression of cholesterol 7 alpha-hydroxylase mRNA by TCA. | Taurocholic Acid | cytochrome P450 family 7 subfamily A member 1 | Rattus norvegicus |