Pub. Date : 1996 Aug 15
PMID : 8761472
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Stimulation for 4 min with PMA (1 microM) or insulin (10 nM) increased levels of PtdIns(3,4,5)P3 approx. | phosphatidylinositol 3,4,5-triphosphate | insulin | Homo sapiens |
2 | In summary, these results demonstrate: (1) that PMA and insulin stimulate PtdIns(3,4,5)P3 production by distinct mechanisms in 3T3-L1 adipocytes, and (2) that stimulation of PtdIns(3,4,5)P3 production by PMA is likely to be important in signalling pathways leading from PMA stimulation to end-point responses such as glucose transport. | phosphatidylinositol 3,4,5-triphosphate | insulin | Homo sapiens |
3 | In summary, these results demonstrate: (1) that PMA and insulin stimulate PtdIns(3,4,5)P3 production by distinct mechanisms in 3T3-L1 adipocytes, and (2) that stimulation of PtdIns(3,4,5)P3 production by PMA is likely to be important in signalling pathways leading from PMA stimulation to end-point responses such as glucose transport. | phosphatidylinositol 3,4,5-triphosphate | insulin | Homo sapiens |