Title : In vivo exposure to NO2 reduces TNF and IL-6 production by endotoxin-stimulated alveolar macrophages.

Pub. Date : 1996 Jul

PMID : 8760143






3 Functional Relationships(s)
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1 In vivo exposure to NO2 reduces TNF and IL-6 production by endotoxin-stimulated alveolar macrophages. Nitrogen Dioxide tumor necrosis factor-like Rattus norvegicus
2 TNF and IL-6 production was significantly decreased (four-to sixfold) in the cell lysate of alveolar macrophages isolated from rats exposed to NO2. Nitrogen Dioxide tumor necrosis factor-like Rattus norvegicus
3 We can conclude that rats exposed to NO2 produce less TNF and IL-6 and that this might be related to increased PGE2 production and increased expression of TNF-R1. Nitrogen Dioxide tumor necrosis factor-like Rattus norvegicus