Title : Influence of diet free of NAD-precursors on acetaminophen hepatotoxicity in mice.

Pub. Date : 1996 Jan

PMID : 8742498






2 Functional Relationships(s)
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1 Recently, we demonstrated the hepatoprotective effects of nicotinic acid amide, a selective inhibitor of poly(ADP-ribose) polymerase (PARP; EC 2.4.2.30) on mice suffering from acetaminophen (AAP)-hepatitis, suggesting that the AAP-induced liver injury involves a step which depends on adenoribosylation. Niacinamide poly (ADP-ribose) polymerase family, member 1 Mus musculus
2 Recently, we demonstrated the hepatoprotective effects of nicotinic acid amide, a selective inhibitor of poly(ADP-ribose) polymerase (PARP; EC 2.4.2.30) on mice suffering from acetaminophen (AAP)-hepatitis, suggesting that the AAP-induced liver injury involves a step which depends on adenoribosylation. Niacinamide poly (ADP-ribose) polymerase family, member 1 Mus musculus