Title : Stereoselectivity of 8-OH-DPAT enantiomers at cloned human 5-HT1D receptor sites.

Pub. Date : 1996 Apr 4

PMID : 8741179






1 Functional Relationships(s)
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1 R(+)-8-OH-DPAT demonstrated potent intrinsic activity (EC50 value: 30 nM) at 5-HT1D alpha receptor sites, its maximal effect being comparable to that of sumatriptan. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine receptor 1D Homo sapiens