Title : Inhibitor-induced changes in the intrinsic fluorescence of human cyclooxygenase-2.

Pub. Date : 1996 Aug 20

PMID : 8718891






1 Functional Relationships(s)
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1 The steady state tryptophan fluorescence of apo-human cyclooxygenase-2 (hCox-2) is quenched approximately 40%-50% by the slow binding inhibitors diclofenac, indomethacin, ketoprofen, NS-398, and DuP-697. Diclofenac mitochondrially encoded cytochrome c oxidase II Homo sapiens