Title : Synergistic activation of PtdIns 3-kinase by tyrosine-phosphorylated peptide and beta gamma-subunits of GTP-binding proteins.

Pub. Date : 1996 Jul 15

PMID : 8713074






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Stimulation of differentiated THP-1 cells by insulin led to rapid accumulation of PtdIns(3,4,5)P3, a product of PtdIns 3-kinase. phosphatidylinositol 3,4,5-triphosphate insulin Homo sapiens
2 The combination of insulin and fMLP induced more PtdIns(3,4,5)P3 production than the sum of the individual effects. phosphatidylinositol 3,4,5-triphosphate insulin Homo sapiens